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Baclofen is used for treating spasm of skeletal muscles, muscle clonus, cramping of muscles, rigidity, spinal cord injury and pain caused by disorders such as multiple sclerosis. Baclofen acts by relaxing skeletal muscles, the muscles that move the skeleton (and also called striated muscle).
Baclofen may interact with next medicines and products such as alcohol, antihistamines, medicines for depression, anxiety, and other mental conditions, medicines for pain like codeine, oxycodone, tramadol, and propoxyphene, medicines for sleep, phenobarbital. Use of Baclofen with other drugs may lead to additional reduction in brain function. For example, the use of Baclofen and tricyclic antidepressants together may cause muscle weakness; the use of Baclofen and monoamine oxidase inhibitors can result in greater depression of brain function as well as low blood pressure.
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Your doctor needs to know you medical history, especially about kidney disease, diabetes, seizures, stroke, an unusual or allergic reaction to Baclofen, other medicines, foods, dyes, or preservatives. You should tell you doctor if you are pregnant or trying to get pregnant and if you are breast-feeding. If you suddenly stop taking your medicine, you may develop a severe reaction. The dose will be slowly lowered over time to avoid any side effects and your doctor have to control this process. Follow the advice of your doctor. You may get drowsy or dizzy when you first start taking the medicine or change doses. You should stand or sit up slowly. Do not drive, use machinery, or do anything that may need your attention and can be dangerous. Stop this kind of activity until you know how the medicine affects you.
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