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In children younger than 12 y.o., hypersensitivity to Nexium or to any other benzimidazole medication such as mebendazole (Vermox) and albendazole (Albenza), and in patients treated with atazanavir.
Nexium is a specific inhibitor of a proton pump (PPIs) of the parietal cells of the mucous layer of stomach. It is a form of Prilosec (Omeprazole). It is accumulated and transformed into an active form in the secretory tubules where it inhibits secretion of hydrochloric acid. Nexium is used to treat gastroesophageal reflux disease (GERD), Zollinger-Ellison syndrome, promote healing of erosive esophagitis, eradication of Helicobacter pylori together with antibiotics, preventive therapy of ulcers after treatment with anti-inflammatory non-steroid medications.
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